Green tea molecule can break protein tangles in the brain that cause Alzheimer’s disease

Scientists at UCLA have used a molecule found in green tea to identify additional molecules that could break protein tangles in the brain thought to cause Alzheimer’s and similar diseases. The green tea molecule, EGCG, is known to break down tau fiber -; long, multilayered filaments that form tangles that attack neurons, causing them to … Read more

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

Scientists have shown how tumor cells evade immune therapy by generating unique, temporary cell-in-cell structures, leaving the inner cells intact and able to revert to individual tumor cells. These findings, published today in eLife, offer a new theory of how tumor cells avoid destruction by the immune system. They may also inform the development of … Read more

Humanized zebrafish could help search for MS drugs

The zebrafish serves as a model organism for researchers around the world: it can be used to study important physiological processes that also take place in a similar form in the human body. It is therefore routinely used in the search for possible active substances against diseases. Researchers from the University of Bonn have now … Read more

BU researcher wins highly competitive prizes to study the role of proteases in the regulation of cellular defense

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases. It is extremely rare for an early … Read more

New insights into how the circadian clock can promote healing after traumatic brain injury

A type of brain cell that can self-renew is regulated by circadian rhythms, providing important insights into how the body’s internal clock may promote healing after traumatic brain injury (TBI), according to new research from Children’s National Hospital. Released in the last issue of eNeuro, the findings open new avenues of research for future TBI … Read more

Soy protein diet increases susceptibility to Clostridioides difficile infection

According to a recent study published in the journal Mobile Reportsa diet rich in soy protein boosts human health Clostridioides difficile sensitivity by increasing the levels of amino acids (AAs) in the gut and promoting the growth of Lactobacillus. Lactobacillusin turn digest soy protein to produce amino acids, which again It is difficult, and therefore, … Read more

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational MedicineResearchers in the United States have designed a bivalent vaccine against coronavirus disease 2019 (COVID-19) on the messenger ribonucleic acid (mRNA) platform. This mRNA lipid nanoparticle vaccine (LNP) encoded a full-length nucleocapsid (N) protein of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ancestral strain … Read more

Gut microbiome associated with multiple sclerosis risk and disease development

An international research consortium led by scientists from UC San Francisco has shown significant differences between the gut bacteria profiles of multiple sclerosis (MS) patients and healthy individuals, as well as between MS patients receiving different drug treatments. While some of these changes have been reported before, most are reported for the first time. The … Read more

Neisseria species are associated with worsening bronchiectasis in patients, study shows

A team of international scientists led by Nanyang Technological University, Singapore (NTU Singapore) has found that: Neisseria – a genus of bacteria that lives in the human body – is not as harmless as previously thought and can cause infections in patients with bronchiectasis, asthma and chronic obstructive pulmonary disease (COPD). In a groundbreaking study, … Read more

Experimental drug prolongs survival, improves muscle function in mice with severe Duchenne muscular dystrophy

Researchers at Johns Hopkins Medicine report that an experimental drug first developed to treat kidney disease prolongs survival and improves muscle function in mice genetically engineered to develop a severe form of Duchenne muscular dystrophy (DMD). According to the Muscular Dystrophy Association (MDA), DMD affects 1 in 5,000 live male births and results in severe … Read more